PAR6G Polyclonal Antibody

Ab type

Primary antibody

Background

The pseudo-CRIB domain together with the PDZ domain is required for the interaction with Rho small GTPases.,Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.,Belongs to the PAR6 family.,Contains 1 OPR domain.,Contains 1 PDZ (DHR) domain.,Contains 1 pseudo-CRIB domain.,subunit:Interacts with PARD3 (Probable). Interacts with GTP-bound forms of CDC42, ARHQ/TC10 and RAC1. Interacts with the N-terminal part of PRKCI and PRKCZ.,tissue specificity:Widely expressed, with a higher expression in fetal and adult kidney.,

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human protein . at AA range: 240-320

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Partitioning defective 6 homolog gamma ;PAR-6 gamma;PAR6D