PAR4 Polyclonal Antibody

Ab type

Primary antibody

Background

The tumor suppressor WT1 represses and activates transcription. Pro-apoptotic WT1 regulator encoded by PAWR is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. Pro-apoptotic WT1 regulator is specifically upregulated during apoptosis of prostate cells.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Prostate Apoptosis Response protein-4. AA range:291-340

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

36568

synonyms

PAWR; PAR4; PRKC apoptosis WT1 regulator protein; Prostate apoptosis response 4 protein; Par-4