PAIP1 Antibody

Size

100ul

Clone Number

Aliases

MGC12360 antibody; OTTHUMP00000221601 antibody; OTTMUSP00000026880 antibody; PABC1 interacting protein 1 antibody; PABP interacting protein 1 antibody; PABP-interacting protein 1 antibody; PAIP 1 antibody; PAIP-1 antibody; Paip1 antibody; PAIP1_HUMAN antibody; Poly(A) binding protein interacting protein 1 antibody; Poly(A)-binding protein-interacting protein 1 antibody; Polyadenylate binding protein interacting protein 1 antibody; Polyadenylate-binding protein-interacting protein 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9H074

Immunogen

Recombinant Human Polyadenylate-binding protein-interacting protein 1 protein (1-260AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB; Recommended dilution: WB:1:200-1:1000

Background

Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PAIP1

Research Areas

Epigenetics and Nuclear Signaling