PAG1 Antibody

Size

100ug

Clone Number

Aliases

CBP antibody; Csk binding protein antibody; Csk-binding protein antibody; FLJ37858 antibody; MGC138364 antibody; PAG 1 antibody; PAG antibody; PAG1 antibody; PAG1_HUMAN antibody; Phosphoprotein associated with glycosphingolipid enriched microdomains 1 antibody; Phosphoprotein associated with glycosphingolipid enriched microdomains antibody; Phosphoprotein associated with glycosphingolipid microdomains 1 antibody; Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 antibody; Protein Associated with Glycosphingolipid Enriched Microdomains antibody; Transmembrane adapter protein PAG antibody; Transmembrane phosphoprotein Cbp antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NWQ8

Immunogen

Recombinant Human Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 protein (97-432AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PAG1

Research Areas

Signal transduction