PACS1 Antibody

Size

100ug

Clone Number

Aliases

Cytosolic sorting protein PACS1 antibody; PACS 1 antibody; PACS-1 antibody; Pacs1 antibody; PACS1_HUMAN antibody; Phosphofurin acidic cluster sorting protein 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6VY07

Immunogen

Recombinant Human Phosphofurin acidic cluster sorting protein 1 protein (757-905AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Coat protein that is involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. Controls the endosome-to-Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the adapter-protein complex-1 (AP-1) of endosomal clathrin-coated membrane pits. Involved in HIV-1 nef-mediated removal of MHC-I from the cell surface to the TGN.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PACS1

Research Areas

Metabolism; Microbiology; Signal transduction