p68 RNA Helicase(Phospho Tyr593) Polyclonal Antibody

Ab type

Primary antibody

Background

DEAD box proteins| characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD)| are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure| such as translation initiation| nuclear and mitochondrial splicing| and ribosome and spliceosome assembly. Based on their distribution patterns| some members of this family are believed to be involved in embryogenesis| spermatogenesis| and cellular growth and division. This gene encodes a DEAD box protein| which is a RNA-dependent ATPase| and also a proliferation-associated nuclear antigen| specifically reacting with the simian virus 40 tumor antigen. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human DDX5/DEAD-box Protein 5 around the phosphorylation site of Tyr593. AA range:565-614

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

69148

synonyms

Probable ATP-dependent RNA helicase DDX5; DDX5; G17P1; HELR; HLR1; Probable ATP-dependent RNA helicase DDX5; DEAD box protein 5; RNA helicase p68