P4HTM Antibody

Size

100ug

Clone Number

Aliases

EGLN4 antibody; HIF PH4 antibody; HIF Prolyl Hydroxylase 4 antibody; HIF prolyl hydroxylase PH 4 antibody; HIF prolyl hydroxylase PH4 antibody; HIF-PH4 antibody; HIF-prolyl hydroxylase 4 antibody; HIFPH4 antibody; HPH 4 antibody; HPH-4 antibody; Hypoxia inducible factor prolyl 4 hydroxylase antibody; Hypoxia-inducible factor prolyl hydroxylase 4 antibody; P4H with transmembrane domain antibody; P4H-TM antibody; P4htm antibody; P4HTM_HUMAN antibody; PH 4 antibody; PH4 antibody; PHD 4 antibody; Proline 4 hydroxylase antibody; prolyl 4-hydroxylase antibody; Transmembrane prolyl 4-hydroxylase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NXG6

Immunogen

Recombinant Human Transmembrane prolyl 4-hydroxylase protein (82-563AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at \'Pro-402\' and \'Pro-564\'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

P4HTM

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cardiovascular