OPRL1 Antibody

Size

100ug

Clone Number

Aliases

H.sapiens mRNA for ORL1 receptor antibody; Kappa type 3 opioid receptor antibody; Kappa-type 3 opioid receptor antibody; kappa3-related opioid receptor antibody; KOR 3 antibody; KOR-3 antibody; KOR3 antibody; LC132 receptor like antibody; LC132 receptor; rat; homolog of antibody; MGC34578 antibody; Nociceptin receptor antibody; Nociceptin/orphanin FQ (N/OFQ) peptide receptor antibody; NOCIR antibody; NOP antibody; OOR antibody; Opiate receptor like 1 antibody; Opiod receptor like 1 antibody; Oprl1 antibody; OPRX_HUMAN antibody; ORL1 antibody; Orphanin FQ receptor antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P41146

Immunogen

Recombinant Human Nociceptin receptor protein (323-370AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:200-1:500

Background

G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

OPRL1

Research Areas

Neuroscience; Metabolism; Signal transduction