OFD1 Antibody

Size

100ug

Clone Number

Aliases

71 7A antibody; 717A antibody; CXorf5 antibody; JBTS10 antibody; Ofd1 antibody; OFD1_HUMAN antibody; oral facial digital syndrome 1 antibody; Oral-facial-digital syndrome 1 protein antibody; OTTHUMP00000022941 antibody; Protein 71-7A antibody; RGD1562231 antibody; SGBS2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O75665

Immunogen

Recombinant Human Oral-facial-digital syndrome 1 protein (598-771AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Background

Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis. Only OFD1 localized at the centriolar satellites is removed by autophagy, which is an important step in the ciliogenesis regulation (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

OFD1

Research Areas

Tags & Cell Markers; Stem cells