OCT4 Monoclonal Antibody

Size

100ul

Clone Number

2H41D8

Aliases

POU domain, class 5, transcription factor 1 (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3), POU5F1, OCT3 OCT4 OTF3

Immunogen Species

Human

UniProt ID

Q01860

Immunogen

Recombinant Human POU domain, class 5, transcription factor 1 protein (1-360AA)

Raised in

Mouse

Species Reactivity

Human, Mouse, Rat

Tested Applications

ELISA, WB, IHC, IF, FC; Recommended dilution: WB:1:500-1:10000, IHC:1:50-1:200, IF:1:50-1:200

Background

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

Clonality

Monoclonal

Isotype

IgG2b

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

OCT4

Research Areas

Epigenetics and Nuclear Signaling