OCRL Antibody, FITC conjugated

Size

100ug

Clone Number

Aliases

EC 3.1.3.36 antibody; Inositol polyphosphate 5 phosphatase OCRL 1 antibody; Inositol polyphosphate 5 phosphatase OCRL1 antibody; Inositol polyphosphate 5-phosphatase OCRL-1 antibody; INPP5F antibody; LOCR antibody; Lowe oculocerebrorenal syndrome protein antibody; NPHL2 antibody; OCRL 1 antibody; OCRL antibody; OCRL_HUMAN antibody; OCRL1 antibody; Oculocerebrorenal syndrome of Lowe antibody; Phosphatidylinositol polyphosphate 5 phosphatase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q01968

Immunogen

Recombinant Human Inositol polyphosphate 5-phosphatase OCRL-1 protein (121-271AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

Background

Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate (PubMed:25869668, PubMed:7761412, PubMed:9430698). May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly (PubMed:22228094, PubMed:22543976).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

FITC

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

OCRL

Research Areas

Cancer; Metabolism; Signal transduction