OCA2 Antibody

Size

100ug

Clone Number

Aliases

BEY antibody; BEY1 antibody; BEY2 antibody; BOCA antibody; D15S12 antibody; EYCL antibody; EYCL2 antibody; EYCL3 antibody; eye color 2 (central brown) antibody; eye color 3 (brown) antibody; hair color 3 (brown) antibody; HCL3 antibody; Melanocyte-specific transporter protein antibody; OCA2 antibody; oculocutaneous albinism II antibody; oculocutaneous albinism II (pink-eye dilution homolog; mouse) antibody; P antibody; P protein antibody; P_HUMAN antibody; PED antibody; Pink eyed dilution protein homolog antibody; Pink-eyed dilution protein homolog antibody; SHEP1 antibody; total brown iris pigmentation antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q04671

Immunogen

Recombinant Human P protein (2-136AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Could be involved in the transport of tyrosine, the precursor to melanin synthesis, within the melanocyte. Regulates the pH of melanosome and the melanosome maturation. One of the components of the mammalian pigmentary system. Seems to regulate the post-translational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis. May serve as a key control point at which ethnic skin color variation is determined. Major determinant of brown and/or blue eye color.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

OCA2

Research Areas

Tags & Cell Markers; Metabolism; Signal transduction