OB-cadherin Polyclonal Antibody

Ab type

Primary antibody

Background

CDH11 encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CDH11. AA range:421-470

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

87965

synonyms

CDH11; Cadherin-11; OSF-4; Osteoblast cadherin; OB-cadherin