NUT Polyclonal Antibody

Ab type

Primary antibody

Background

A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with BRD4 which produces a BRD4-NUT fusion protein.,disease:A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with BRD3 which produces a BRD3-NUT fusion protein.,PTM:Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export.,Belongs to the FAM22 family.,subcellular location:Shuttles between nucleus and cytoplasm.,tissue specificity:Specifically expressed in testis.,

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human NUT. at AA range: 1082-1131

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

NUT; Protein NUT; Nuclear protein in testis