NUMB Antibody

Size

100ul

Clone Number

Aliases

c14_5527 antibody; C14orf41 antibody; FLJ31314 antibody; h Numb antibody; h-Numb antibody; Numb antibody; Numb homolog (Drosophila) antibody; Numb homolog antibody; Numb protein homolog antibody; NUMB_HUMAN antibody; Protein numb homolog antibody; Protein S171 antibody; S171 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P49757

Immunogen

Recombinant Human Protein numb homolog protein (532-651AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB; Recommended dilution: WB:1:1000-1:5000

Background

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NUMB

Research Areas

Neuroscience; Stem cells