NUAK2 Antibody

Size

100ul

Clone Number

Aliases

DKFZp434J037 antibody; DKFZp686F01113 antibody; FLJ90349 antibody; NUAK family SNF1 like kinase 2 antibody; NUAK family SNF1-like kinase 2 antibody; Nuak2 antibody; NUAK2_HUMAN antibody; Omphalocele kinase 2 antibody; SNARK antibody; SNF1/AMP activated protein kinase antibody; SNF1/AMP kinase related kinase antibody; SNF1/AMP kinase-related kinase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9H093

Immunogen

Recombinant Human NUAK family SNF1-like kinase 2 protein (479-628AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate \\\'Ser-464\\\' of LATS1.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NUAK2

Research Areas

Cancer; Signal transduction