NTN Polyclonal Antibody

Ab type

Primary antibody

Background

NRTN encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. Neurturin signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human NRTN. AA range:111-160

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

22405

synonyms

NRTN; Neurturin