NTE Polyclonal Antibody

Ab type

Primary antibody

Background

PNPLA6 encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The patatin like phospholipase domain containing 6 is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human PNPLA6. AA range:102-151

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

149995

synonyms

PNPLA6; NTE; Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6