NTCP2 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism| so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines| such as familial hypertriglyceridemia (FHTG).

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human NTCP2

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

38280

synonyms

NTCP2