NTAN1 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg| which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8| 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human NTAN1

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

34100

synonyms

NTAN1