NSUN2 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

5 methycytoisine methyltransferase antibody; D13Wsu123e antibody; FLJ20303 antibody; hTrm4 antibody; MISU antibody; Myc induced SUN domain containing protein antibody; NOL1/NOP2/Sun domain family 2 antibody; NOL1/NOP2/Sun domain family 2 protein antibody; NOL1/NOP2/Sun domain family member 2 antibody; NSUN 2 antibody; NSUN2 antibody; NSUN2_HUMAN antibody; SAKI antibody; Substrate of AIM1/Aurora kinase B antibody; TRM4 antibody; tRNA (cytosine 5 ) methyltransferase antibody; tRNA (cytosine 5 ) methyltransferase NSUN2 antibody; tRNA (cytosine(34)-C(5))-methyltransferase antibody; tRNA (cytosine-5-)-methyltransferase antibody; tRNA methyltransferase 4 homolo antibody; tRNA methyltransferase 4 homolog antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q08J23

Immunogen

Recombinant Human tRNA (cytosine(34)-C(5))-methyltransferase protein (432-509AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NSUN2

Research Areas

Epigenetics and Nuclear Signaling