• IHC staining of FFPE human breast carcinoma tissue with Migfilin-1 antibody (clone FBLIM1/4600) at 2ug/ml. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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NSJ Bioreagents

V9720-20UG

Migfilin-1 Antibody / FLNB / Filamin B / FBLIM1, 20 ug

Migfilin-1 Antibody / FLNB / Filamin B / FBLIM1, 20 ug

$259.00 USD
$259.00 USD
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Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion. [UniProt]

Specifications

Catalog No V9720-20UG
Family Primary antibody
Qty 20 ug
Formulation 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format Purified
Clone FBLIM1/4600
Host Animal Mouse
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Species Reactivity Human
Application WB, IF, IHC-P
Application Details Western blot: 1-2ug/ml,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
Application Note Optimal dilution of the Migfilin-1 antibody should be determined by the researcher.
Localization Cytoplasm
Immunogen Recombinant full-length human protein was used as the immunogen for the Migfilin-1 antibody.
Purity Protein A/G affinity
Storage Aliquot the Migfilin-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This Migfilin-1 antibody is available for research use only.
Uniprot # Q8WUP2
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/migfilin-1-antibody-flnb-filamin-b-fblim1-fblim14600-v9720
Title Migfilin-1 Antibody / FLNB / Filamin B / FBLIM1
Description Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion. [UniProt]
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