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NSJ Bioreagents
SKU:V9720-100UG
Migfilin-1 Antibody / FLNB / Filamin B / FBLIM1, 100 ug
Migfilin-1 Antibody / FLNB / Filamin B / FBLIM1, 100 ug
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Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion. [UniProt]
Specifications
| Catalog No | V9720-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | FBLIM1/4600 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Species Reactivity | Human |
| Application | WB, IF, IHC-P |
| Application Details | Western blot: 1-2ug/ml,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the Migfilin-1 antibody should be determined by the researcher. |
| Localization | Cytoplasm |
| Immunogen | Recombinant full-length human protein was used as the immunogen for the Migfilin-1 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the Migfilin-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Migfilin-1 antibody is available for research use only. |
| Uniprot # | Q8WUP2 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/migfilin-1-antibody-flnb-filamin-b-fblim1-fblim14600-v9720 |
| Title | Migfilin-1 Antibody / FLNB / Filamin B / FBLIM1 |
| Description | Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion. [UniProt] |
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