• IHC staining of FFPE human stomach with MICA antibody (clone MICA/4442). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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NSJ Bioreagents

V9702-20UG

MICA Antibody, 20 ug

MICA Antibody, 20 ug

$259.00 USD
$259.00 USD
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MICA and MICB are stress-induced antigens that are related to major histocompatibility complex (MHC) class I molecules. MICA and MICB are frequently expressed in epithelial tumors. These highly glycosylated cell surface proteins are stably expressed without conventional class I peptide ligands or association with γδ T cells expressing variable TCRs, suggesting that these antigens may play a central role in the signaling of cellular distress to evoke immune responses in the intestinal epithelium.

Specifications

Catalog No V9702-20UG
Family Primary antibody
Qty 20 ug
Formulation 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format Purified
Clone MICA/4442
Host Animal Mouse
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Species Reactivity Human
Application WB, IHC-P
Application Details Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
Application Note Optimal dilution of the MICA antibody should be determined by the researcher.
Localization Cell surface, Cytoplasm
Immunogen A portion of amino acids 1-200 was used as the immunogen for the MICA antibody.
Purity Protein A/G affinity
Storage Aliquot the MICA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This MICA antibody is available for research use only.
Uniprot # Q29983
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/mica-antibody-mica4442-v9702
Title MICA Antibody
Description MICA and MICB are stress-induced antigens that are related to major histocompatibility complex (MHC) class I molecules. MICA and MICB are frequently expressed in epithelial tumors. These highly glycosylated cell surface proteins are stably expressed without conventional class I peptide ligands or association with γδ T cells expressing variable TCRs, suggesting that these antigens may play a central role in the signaling of cellular distress to evoke immune responses in the intestinal epithelium.
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