NSJ Bioreagents
SKU:V9679-20UG
Neprilysin Antibody / CD10, 20 ug
Neprilysin Antibody / CD10, 20 ug
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Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
Specifications
| Catalog No | V9679-20UG |
|---|---|
| Family | Primary antibody |
| Qty | 20 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | MME/6461 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2b, kappa |
| Species Reactivity | Human |
| Application | IHC-P, WB |
| Application Details | Immunohistochemistry (FFPE): 1-2ug/ml,Western blot: 2-4ug/ml |
| Application Note | Optimal dilution of the Neprilysin antibody should be determined by the researcher. |
| Localization | Cell surface, Cytoplasm |
| Immunogen | A portion of amino acids 54-181 was used as the immunogen for the Neprilysin antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the Neprilysin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Neprilysin antibody is available for research use only. |
| Uniprot # | P08473 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/neprilysin-antibody-cd10-mme6461-v9679 |
| Title | Neprilysin Antibody / CD10 |
| Description | Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. |
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