NSJ Bioreagents
SKU:V9669-100UG
LH beta Antibody / Luteinizing Hormone beta, 100 ug
LH beta Antibody / Luteinizing Hormone beta, 100 ug
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LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
Specifications
| Catalog No | V9669-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | rLHb/1613 |
| Host Animal | Mouse |
| Clonality | Recombinant Mouse Monoclonal |
| Isotype | Mouse IgG1, kappa |
| Species Reactivity | Human |
| Application | IHC-P |
| Application Details | Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the LH beta antibody should be determined by the researcher. |
| Localization | Cytoplasm, Secreted |
| Immunogen | Recombinant full-length human protein was used as the immunogen for the LH beta antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the LH beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This LH beta antibody is available for research use only. |
| Uniprot # | P01229 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/lh-beta-antibody-luteinizing-hormone-beta-rlhb1613-v9669 |
| Title | LH beta Antibody / Luteinizing Hormone beta |
| Description | LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease. |
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