NSJ Bioreagents
SKU:V9626-100UG
STING1 Antibody / TMEM173, 100 ug
STING1 Antibody / TMEM173, 100 ug
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TMEM17 (transmembrane protein 173) is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Specifications
| Catalog No | V9626-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | STING1/7431 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG |
| Species Reactivity | Human |
| Application | IHC-P |
| Application Details | Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the STING1 antibody should be determined by the researcher. |
| Localization | Cytoplasm |
| Immunogen | A portion of amino acids 190-290 was used as the immunogen for the STING1 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the STING1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This STING1 antibody is available for research use only. |
| Uniprot # | Q86WV6 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/sting1-antibody-tmem173-sting17431-v9626 |
| Title | STING1 Antibody / TMEM173 |
| Description | TMEM17 (transmembrane protein 173) is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
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