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NSJ Bioreagents

SKU:V9623-100UG

Bcl6 Antibody, 100 ug

Bcl6 Antibody, 100 ug

Regular price $559.00 USD
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Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( LH ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.

Specifications

Catalog No V9623-100UG
Family Primary antibody
Qty 100 ug
Formulation 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format Purified
Clone PCRP-BCL6-1E2
Host Animal Mouse
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Species Reactivity Human
Application FACS, IF
Application Details Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml
Application Note Optimal dilution of the Bcl6 antibody should be determined by the researcher.
Localization Nucleus, Cytoplasm
Immunogen Recombinant full-length human protein was used as the immunogen for the Bcl6 antibody.
Purity Protein A/G affinity
Storage Aliquot the Bcl6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This Bcl6 antibody is available for research use only.
Uniprot # P41182
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/bcl6-antibody-pcrp-bcl6-1e2-v9623
Title Bcl6 Antibody
Description Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( LH ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
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