NSJ Bioreagents
SKU:V9620-100UG
Angiotensin Converting Enzyme Antibody / ACE, 100 ug
Angiotensin Converting Enzyme Antibody / ACE, 100 ug
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This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.
Specifications
| Catalog No | V9620-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | ACE/3764 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Species Reactivity | Human |
| Application | ELISA, IHC-P |
| Application Details | ELISA (order BSA-free format for coating),Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the Angiotensin Converting Enzyme antibody should be determined by the researcher. |
| Localization | Cell Surface |
| Immunogen | Full-length recombinant human protein was used as the immunogen for the Angiotensin Converting Enzyme antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the Angiotensin Converting Enzyme antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Angiotensin Converting Enzyme antibody is available for research use only. |
| Uniprot # | P12821 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/angiotensin-converting-enzyme-antibody-ace-ace3764-v9620 |
| Title | Angiotensin Converting Enzyme Antibody / ACE |
| Description | This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
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