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NSJ Bioreagents
SKU:V9613-20UG
JAZF1 Antibody, 20 ug
JAZF1 Antibody, 20 ug
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$259.00 USD
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JAZF1 (juxtaposed with another zinc finger protein 1), also known as TIP27 (TAK1-interacting protein 27) or ZNF802 (zinc finger protein 802), is a 243 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Existing as multiple alternatively spliced isoforms, JAZF1 interacts with the nuclear orphan receptor TR4 and is thought to function as a transcriptional repressor, effectively down-regulation the expression of TR4. Chromosomal aberrations in the gene encoding JAZF1 are associated with the pathogenesis of endometrial stromal tumors, suggesting a role for JAZF1 in carcinogenesis.
Specifications
| Catalog No | V9613-20UG |
|---|---|
| Family | Primary antibody |
| Qty | 20 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | PCRP-JAZF1-1C2 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2a |
| Species Reactivity | Human |
| Application | FACS, IF, WB, IHC-P |
| Application Details | Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the JAZF1 antibody should be determined by the researcher. |
| Localization | Nucleus |
| Immunogen | A portion of amino acids 1-130 was used as the immunogen for the JAZF1 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the JAZF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This JAZF1 antibody is available for research use only. |
| Uniprot # | Q86VZ6 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/jazf1-antibody-pcrp-jazf1-1c2-v9613 |
| Title | JAZF1 Antibody |
| Description | JAZF1 (juxtaposed with another zinc finger protein 1), also known as TIP27 (TAK1-interacting protein 27) or ZNF802 (zinc finger protein 802), is a 243 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Existing as multiple alternatively spliced isoforms, JAZF1 interacts with the nuclear orphan receptor TR4 and is thought to function as a transcriptional repressor, effectively down-regulation the expression of TR4. Chromosomal aberrations in the gene encoding JAZF1 are associated with the pathogenesis of endometrial stromal tumors, suggesting a role for JAZF1 in carcinogenesis. |
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