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NSJ Bioreagents
SKU:V9582-20UG
Recombinant Sex Hormone Binding Globulin Antibody / SHBG, 20 ug
Recombinant Sex Hormone Binding Globulin Antibody / SHBG, 20 ug
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Recognizes a protein of 45kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Specifications
| Catalog No | V9582-20UG |
|---|---|
| Family | Primary antibody |
| Qty | 20 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | rSHBG/4447 |
| Host Animal | Mouse |
| Clonality | Recombinant Mouse Monoclonal |
| Isotype | Mouse IgG2a, kappa |
| Species Reactivity | Human |
| Application | ELISA, IHC-P |
| Application Details | ELISA (order BSA-free format for coating),Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the recombinant Sex Hormone Binding Globulin antibody should be determined by the researcher. |
| Localization | Cytoplasmic & Extracellular (Secreted) |
| Immunogen | Recombinant full-length human protein was used as the immunogen for the recombinant Sex Hormone Binding Globulin antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the recombinant Sex Hormone Binding Globulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This recombinant Sex Hormone Binding Globulin antibody is available for research use only. |
| Uniprot # | P04278 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/recombinant-sex-hormone-binding-globulin-antibody-shbg-rshbg4447-v9582 |
| Title | Recombinant Sex Hormone Binding Globulin Antibody / SHBG |
| Description | Recognizes a protein of 45kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis. |
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