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NSJ Bioreagents

SKU:V9560-20UG

CCL8 Antibody / MCP2, 20 ug

CCL8 Antibody / MCP2, 20 ug

Regular price $259.00 USD
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This anti-microbial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.

Specifications

Catalog No V9560-20UG
Family Primary antibody
Qty 20 ug
Formulation 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format Purified
Clone CCL8/3683
Host Animal Mouse
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2c, kappa
Species Reactivity Human
Application IHC-P
Application Details Immunohistochemistry (FFPE): 1-2ug/ml
Application Note Optimal dilution of the CCL8 antibody should be determined by the researcher.
Localization Secreted
Immunogen A portin of amino acids 1-99 from the human protein was used as the immunogen for the CCL8 antibody.
Purity Protein A/G affinity
Storage Aliquot the CCL8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This CCL8 antibody is available for research use only.
Uniprot # P80075
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/ccl8-antibody-mcp2-ccl83683-v9560
Title CCL8 Antibody / MCP2
Description This anti-microbial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.
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