NSJ Bioreagents
SKU:V9552-20UG
ACE Antibody / Angiotensin I Converting Enzyme, 20 ug
ACE Antibody / Angiotensin I Converting Enzyme, 20 ug
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This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.
Specifications
| Catalog No | V9552-20UG |
|---|---|
| Family | Primary antibody |
| Qty | 20 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | ACE/7004R |
| Host Animal | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | ELISA |
| Application Details | ELISA (order BSA-free format for coating) |
| Application Note | Optimal dilution of the ACE antibody should be determined by the researcher. |
| Localization | Cell Surface |
| Immunogen | A portion of amino acids 652-788 was used as the immunogen for the ACE antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the ACE antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This ACE antibody is available for research use only. |
| Uniprot # | P12821 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/ace-antibody-angiotensin-i-converting-enzyme-ace7004r-v9552 |
| Title | ACE Antibody / Angiotensin I Converting Enzyme |
| Description | This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
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