• IHC staining of FFPE human pancreatic tissue with Vitamin D binding protein antibody (clone VDBP/4482) at 2ug/ml in PBS for 30min RT. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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NSJ Bioreagents

V9504-20UG

Vitamin D binding protein Antibody / VDBP / GC, 20 ug

Vitamin D binding protein Antibody / VDBP / GC, 20 ug

$259.00 USD
$259.00 USD
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Vitamin D-binding protein (DBP) is a multi-functional serum protein that binds to the plasma membranes of numerous cell types and mediates a variety of cellular functions. The locus of the DBP protein (also known as group-specific component protein or GC) is located at human chromosome 4q13.3. DBP functions in organ-specific transportation of vitamin D and its metabolites to the various target organs of the vitamin D endocrine system. In addition, DBP has immunomodulatory properties and is able to bind to the surface of leukocytes. DBP binds to the plasma membrane through a chondroitin sulfate proteoglycan. DBP serves as a co-chemotactic factor for C5a to enhance the chemotactic activity of C5a. DBP can also bind to globular Actin with high affinity and is involved in the clearance of Actin from the blood. DBP plays an important role in osteoclast differentiation. The diverse cellular functions of DBP require its cell surface binding ability to mediate different biological processes.

Specifications

Catalog No V9504-20UG
Family Primary antibody
Qty 20 ug
Formulation 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format Purified
Clone VDBP/4482
Host Animal Mouse
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Species Reactivity Human
Application IHC-P
Application Details Immunohistochemistry (FFPE): 1-2ug/ml
Application Note Optimal dilution of the Vitamin D binding protein antibody should be determined by the researcher.
Localization Secreted
Immunogen A portion of amino acids 35-175 was used as the immunogen for the Vitamin D binding protein antibody.
Purity Protein A/G affinity
Storage Aliquot the Vitamin D binding protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This Vitamin D binding protein antibody is available for research use only.
Uniprot # P02774
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/vitamin-d-binding-protein-antibody-vdbp-gc-vdbp4482-v9504
Title Vitamin D binding protein Antibody / VDBP / GC
Description Vitamin D-binding protein (DBP) is a multi-functional serum protein that binds to the plasma membranes of numerous cell types and mediates a variety of cellular functions. The locus of the DBP protein (also known as group-specific component protein or GC) is located at human chromosome 4q13.3. DBP functions in organ-specific transportation of vitamin D and its metabolites to the various target organs of the vitamin D endocrine system. In addition, DBP has immunomodulatory properties and is able to bind to the surface of leukocytes. DBP binds to the plasma membrane through a chondroitin sulfate proteoglycan. DBP serves as a co-chemotactic factor for C5a to enhance the chemotactic activity of C5a. DBP can also bind to globular Actin with high affinity and is involved in the clearance of Actin from the blood. DBP plays an important role in osteoclast differentiation. The diverse cellular functions of DBP require its cell surface binding ability to mediate different biological processes.
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