NSJ Bioreagents
SKU:V9482-100UG
Fatty Acid Binding Protein 4 Antibody / FABP4, 100 ug
Fatty Acid Binding Protein 4 Antibody / FABP4, 100 ug
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Fatty acid-binding proteins, designated FABPs, are a family of homologous, cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). The human A-FABP gene is organized into 4 exons, maps to chromosome 8q21.13, and encodes a 132 amino acid protein. A-FABP protein comprises approximately 1% of the total cytosolic protein in human adipose tissue.
Specifications
| Catalog No | V9482-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | FABP4/4422 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Species Reactivity | Human |
| Application | IHC-P |
| Application Details | Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the Fatty Acid Binding Protein 4 antibody should be determined by the researcher. |
| Localization | Cytoplasm, Nucleus |
| Immunogen | A portion of amino acids 1-132 was used as the immunogen for the Fatty Acid Binding Protein 4 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the Fatty Acid Binding Protein 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Fatty Acid Binding Protein 4 antibody is available for research use only. |
| Uniprot # | P15090 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/fatty-acid-binding-protein-4-antibody-fabp4-fabp44422-v9482 |
| Title | Fatty Acid Binding Protein 4 Antibody / FABP4 |
| Description | Fatty acid-binding proteins, designated FABPs, are a family of homologous, cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). The human A-FABP gene is organized into 4 exons, maps to chromosome 8q21.13, and encodes a 132 amino acid protein. A-FABP protein comprises approximately 1% of the total cytosolic protein in human adipose tissue. |
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