NSJ Bioreagents
SKU:V9460-100UG
Fibronectin 1 Antibody / FN1, 100 ug
Fibronectin 1 Antibody / FN1, 100 ug
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Fibronectins are disulfide-linked, dimeric glycoproteins of ~440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin.
Specifications
| Catalog No | V9460-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | FN1/3569 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2b, kappa |
| Species Reactivity | Human |
| Application | ELISA, IHC-P |
| Application Details | ELISA (order BSA-free format for coating),Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the Fibronectin 1 antibody should be determined by the researcher. |
| Localization | Connective tissue matrix |
| Immunogen | A portion of amino acids 467-595 was used as the immunogen for the Fibronectin 1 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the Fibronectin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Fibronectin 1 antibody is available for research use only. |
| Uniprot # | P02751 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/fibronectin-1-antibody-fn1-fn13569-v9460 |
| Title | Fibronectin 1 Antibody / FN1 |
| Description | Fibronectins are disulfide-linked, dimeric glycoproteins of ~440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin. |
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