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NSJ Bioreagents
SKU:V9450-20UG
Recombinant SF-1 Antibody / Steroidogenic Factor 1 / NR5A1, 20 ug
Recombinant SF-1 Antibody / Steroidogenic Factor 1 / NR5A1, 20 ug
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Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development.SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.
Specifications
| Catalog No | V9450-20UG |
|---|---|
| Family | Primary antibody |
| Qty | 20 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | NR5A1/4368R |
| Host Animal | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG, kappa |
| Species Reactivity | Human |
| Application | IHC-P |
| Application Details | Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the recombinant SF-1 antibody should be determined by the researcher. |
| Localization | Nuclear |
| Immunogen | A recombinant fragment of human SF-1 protein was used as the immunogen for the recombinant SF-1 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the recombinant SF-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This recombinant SF-1 antibody is available for research use only. |
| Uniprot # | Q13285 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/recombinant-sf-1-antibody-steroidogenic-factor-1-nr5a1-nr5a14368r-v9450 |
| Title | Recombinant SF-1 Antibody / Steroidogenic Factor 1 / NR5A1 |
| Description | Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development.SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass. |
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