• IHC staining of FFPE human thyroid tissue with recombinant Cadherin 16 antibody (clone CHD16/7027R) at 2ug/ml in PBS for 30min RT. Negative control inset: PBS used instead of primary antibody to control for secondary Ab binding. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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NSJ Bioreagents

V9442-100UG

Recombinant Cadherin 16 Antibody / CDH16, 100 ug

Recombinant Cadherin 16 Antibody / CDH16, 100 ug

$559.00 USD
$559.00 USD
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This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin/cadherin 16/CDH16. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Specifications

Catalog No V9442-100UG
Family Primary antibody
Qty 100 ug
Formulation 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format Purified
Clone CDH16/7027R
Host Animal Rabbit
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Species Reactivity Human
Application IHC-P, WB
Application Details Immunohistochemistry (FFPE): 1-2ug/ml,Western blot: 2-4ug/ml
Application Note Optimal dilution of the recombinant Cadherin 16 antibody should be determined by the researcher.
Localization Cell surface, Cytoplasm
Immunogen Recombinant human full-length protein was used as the immunogen for the recombinant Cadherin 16 antibody.
Purity Protein A affinity
Storage Aliquot the recombinant Cadherin 16 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This recombinant Cadherin 16 antibody is available for research use only.
Uniprot # O75309
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/recombinant-cadherin-16-antibody-cdh16-cdh167027r-v9442
Title Recombinant Cadherin 16 Antibody / CDH16
Description This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin/cadherin 16/CDH16. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
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