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NSJ Bioreagents
SKU:V9436-100UG
CD27 Antibody, 100 ug
CD27 Antibody, 100 ug
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$559.00 USD
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Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NF B and SAPK/JNK and induces apoptosis.
Specifications
| Catalog No | V9436-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | LPFS2/4178 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Species Reactivity | Human |
| Application | IHC-P, WB |
| Application Details | Immunohistochemistry (FFPE): 1-2ug/ml,Western blot: 2-4ug/ml |
| Application Note | Optimal dilution of the CD27 antibody should be determined by the researcher. |
| Localization | Cell surface |
| Immunogen | A portion of amino acids 28-170 was used as the immunogen for the CD27 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the CD27 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This CD27 antibody is available for research use only. |
| Uniprot # | P26842 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cd27-antibody-lpfs24178-v9436 |
| Title | CD27 Antibody |
| Description | Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NF B and SAPK/JNK and induces apoptosis. |
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