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NSJ Bioreagents
SKU:V9411-20UG
PGR Antibody / Progesterone Receptor, 20 ug
PGR Antibody / Progesterone Receptor, 20 ug
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This MAb is specific to PR/PGR and shows minimal cross-reaction with other members of the family. PR is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect an intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
Specifications
| Catalog No | V9411-20UG |
|---|---|
| Family | Primary antibody |
| Qty | 20 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | PGR/3817 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2b, kappa |
| Species Reactivity | Human |
| Application | IHC-P |
| Application Details | Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the PGR antibody should be determined by the researcher. |
| Localization | Nucleus |
| Immunogen | A portion of amino acids 483-571 was used as the immunogen for the PGR antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the PGR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This PGR antibody is available for research use only. |
| Uniprot # | P06401 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/pgr-antibody-progesterone-receptor-pgr3817-v9411 |
| Title | PGR Antibody / Progesterone Receptor |
| Description | This MAb is specific to PR/PGR and shows minimal cross-reaction with other members of the family. PR is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect an intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues. |
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