NSJ Bioreagents
SKU:V9402-100UG
Recombinant CALD1 Antibody/ Caldesmon / CAD (HMW), 100 ug
Recombinant CALD1 Antibody/ Caldesmon / CAD (HMW), 100 ug
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Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Specifications
| Catalog No | V9402-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | rCALD1/7266 |
| Host Animal | Mouse |
| Clonality | Recombinant Mouse Monoclonal |
| Isotype | Mouse IgG1, kappa |
| Species Reactivity | Human |
| Application | IHC-P |
| Application Details | Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the recombinant CALD1 antibody should be determined by the researcher. |
| Localization | Cytoplasm |
| Immunogen | Recombinant human full-length CALD1 protein was used as the immunogen for the recombinant CALD1 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the recombinant CALD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This recombinant CALD1 antibody is available for research use only. |
| Uniprot # | Q05682 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/recombinant-cald1-antibody-caldesmon-cad-hmw-rcald17266-v9402 |
| Title | Recombinant CALD1 Antibody/ Caldesmon / CAD (HMW) |
| Description | Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction. |
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