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NSJ Bioreagents
SKU:V9388-20UG
AKR1B1 Antibody / Aldose reductase, 20 ug
AKR1B1 Antibody / Aldose reductase, 20 ug
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$259.00 USD
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AKR1B1, also designated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.
Specifications
| Catalog No | V9388-20UG |
|---|---|
| Family | Primary antibody |
| Qty | 20 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | rAKR1B1/7295 |
| Host Animal | Mouse |
| Clonality | Recombinant Mouse Monoclonal |
| Isotype | Mouse IgG1, kappa |
| Species Reactivity | Human |
| Application | IHC-P, WB |
| Application Details | Immunohistochemistry (FFPE): 1-2ug/ml,Western blot: 2-4ug/ml |
| Application Note | Optimal dilution of the AKR1B1 antibody should be determined by the researcher. |
| Localization | Cytoplasm |
| Immunogen | Recombinant human full-length AKR1B1 protein was used as the immunogen for the AKR1B1 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the AKR1B1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This AKR1B1 antibody is available for research use only. |
| Uniprot # | P15121 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/akr1b1-antibody-aldose-reductase-rakr1b17295-v9388 |
| Title | AKR1B1 Antibody / Aldose reductase |
| Description | AKR1B1, also designated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis. |
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