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NSJ Bioreagents
SKU:V9360-100UG
Recombinant CD47 Antibody / IAP / Integrin Associated Protein, 100 ug
Recombinant CD47 Antibody / IAP / Integrin Associated Protein, 100 ug
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This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
Specifications
| Catalog No | V9360-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | rCD47/6589 |
| Host Animal | Mouse |
| Clonality | Recombinant Mouse Monoclonal |
| Isotype | Mouse IgG1, kappa |
| Species Reactivity | Human |
| Application | IHC-P, WB |
| Application Details | Immunohistochemistry (FFPE): 1-2ug/ml,Western blot: 2-4ug/ml |
| Application Note | Optimal dilution of the recombinant CD47 antibody should be determined by the researcher. |
| Localization | Cell Surface |
| Immunogen | Recombinant full-length human protein was used as the immunogen for the recombinant CD47 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the recombinant CD47 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This recombinant CD47 antibody is available for research use only. |
| Uniprot # | Q08722 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/recombinant-cd47-antibody-iap-integrin-associated-protein-rcd476589-v9360 |
| Title | Recombinant CD47 Antibody / IAP / Integrin Associated Protein |
| Description | This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. |
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