• IHC staining of FFPE human prostate carcinoma tissue with recombinant Integrin Associated Protein antibody (clone rCD47/6365). Negative control inset: PBS instead of primary antibody to control for secondary binding. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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NSJ Bioreagents

V9335-20UG

Recombinant Integrin Associated Protein Antibody / IAP / CD47, 20 ug

Recombinant Integrin Associated Protein Antibody / IAP / CD47, 20 ug

$259.00 USD
$259.00 USD
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This antibody reacts with Ig domain of CD47/Integrin Associated Protein/IAP protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. It plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47/IAP may play a role in membrane transport and/or integrin dependent signal transduction.

Specifications

Catalog No V9335-20UG
Family Primary antibody
Qty 20 ug
Formulation 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format Purified
Clone rCD47/6365
Host Animal Mouse
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Species Reactivity Human
Application IHC-P
Application Details Immunohistochemistry (FFPE): 1-2ug/ml
Application Note Optimal dilution of the recombinant Integrin Associated Protein antibody should be determined by the researcher.
Localization Cell surface, cytoplasmic
Immunogen Recombinant full-length human protein was used as the immunogen for the recombinant Integrin Associated Protein antibody.
Purity Protein A/G affinity
Storage Aliquot the recombinant Integrin Associated Protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This recombinant Integrin Associated Protein antibody is available for research use only.
Uniprot # Q08722
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/recombinant-integrin-associated-protein-antibody-iap-cd47-rcd476365-v9335
Title Recombinant Integrin Associated Protein Antibody / IAP / CD47
Description This antibody reacts with Ig domain of CD47/Integrin Associated Protein/IAP protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. It plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47/IAP may play a role in membrane transport and/or integrin dependent signal transduction.
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