NSJ Bioreagents
SKU:V9325-100UG
Recombinant Keratin 8 Antibody / Cytokeratin 8, 100 ug
Recombinant Keratin 8 Antibody / Cytokeratin 8, 100 ug
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Cytokeratin 8 (also called CK8, Keratin 8 and KRT8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium.
Specifications
| Catalog No | V9325-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | KRT8/6472R |
| Host Animal | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, IHC-P |
| Application Details | Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the recombinant Keratin 8 antibody should be determined by the researcher. |
| Localization | Cytoplasmic |
| Immunogen | Recombinant full-length human KRT8 protein was used as the immunogen for the recombinant Keratin 8 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the recombinant Keratin 8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This recombinant Keratin 8 antibody is available for research use only. |
| Uniprot # | P05787 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/recombinant-keratin-8-antibody-cytokeratin-8-krt86472r-v9325 |
| Title | Recombinant Keratin 8 Antibody / Cytokeratin 8 |
| Description | Cytokeratin 8 (also called CK8, Keratin 8 and KRT8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. |
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