• IHC staining of FFPE human colon tissue with Delta 1 Catenin antibody (clone CTNND1/4501) at 2ug/ml in PBS for 30min RT. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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NSJ Bioreagents

V9324-100UG

Delta 1 Catenin Antibody / CTNND1 / p120 Catenin, 100 ug

Delta 1 Catenin Antibody / CTNND1 / p120 Catenin, 100 ug

$559.00 USD
$559.00 USD
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Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin (delta-1-catenin) binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, delta-1-catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins.

Specifications

Catalog No V9324-100UG
Family Primary antibody
Qty 100 ug
Formulation 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format Purified
Clone CTNND1/4501
Host Animal Mouse
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Species Reactivity Human
Application IHC-P
Application Details Immunohistochemistry (FFPE): 2-4ug/ml
Application Note Optimal dilution of the Delta 1 Catenin antibody should be determined by the researcher.
Localization Cell Surface, Cytoplasm
Immunogen A portion of amino acids 138-276 was used as the immunogen for the Delta 1 Catenin antibody.
Purity Protein A/G affinity
Storage Aliquot the Delta 1 Catenin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This Delta 1 Catenin antibody is available for research use only.
Uniprot # O60716
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/delta-1-catenin-antibody-ctnnd1-p120-catenin-ctnnd14501-v9324
Title Delta 1 Catenin Antibody / CTNND1 / p120 Catenin
Description Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin (delta-1-catenin) binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, delta-1-catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins.
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