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NSJ Bioreagents
SKU:V9302-100UG
Recombinant TOP2A Antibody / Topoisomerase II alpha, 100 ug
Recombinant TOP2A Antibody / Topoisomerase II alpha, 100 ug
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$559.00 USD
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It recognizes a 170kDa protein, which is identified as topoisomerase II is also implicated in drug resistance of tumor cells and has been shown to be over-expressed in many human cancers. Decreased expression of Topo IIa is the predominant mechanism of resistance to several chemotherapeutic agents.
Specifications
| Catalog No | V9302-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | rTOP2A/6569 |
| Host Animal | Mouse |
| Clonality | Recombinant Mouse Monoclonal |
| Isotype | Mouse IgG2a, kappa |
| Species Reactivity | Human, Mouse |
| Application | WB, IHC-P |
| Application Details | Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml |
| Application Note | Optimal dilution of the recombinant TOP2A antibody should be determined by the researcher. |
| Localization | Nuclear |
| Immunogen | A portion of amino acids 1352-1493 was used as the immunogen for the recombinant TOP2A antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the recombinant TOP2A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This recombinant TOP2A antibody is available for research use only. |
| Uniprot # | P11388 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/recombinant-top2a-antibody-topoisomerase-ii-alpha-rtop2a6569-v9302 |
| Title | Recombinant TOP2A Antibody / Topoisomerase II alpha |
| Description | It recognizes a 170kDa protein, which is identified as topoisomerase II is also implicated in drug resistance of tumor cells and has been shown to be over-expressed in many human cancers. Decreased expression of Topo IIa is the predominant mechanism of resistance to several chemotherapeutic agents. |
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