NSJ Bioreagents
SKU:V9287-20UG
Smooth Muscle Actin Antibody, 20 ug
Smooth Muscle Actin Antibody, 20 ug
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Actin is a major component of the cytoskeleton and is present in most cell types. It is highly specific to actin from smooth muscles. <strong>This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells.</strong> This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
Specifications
| Catalog No | V9287-20UG |
|---|---|
| Family | Primary antibody |
| Qty | 20 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | rACTA2/1625 |
| Host Animal | Mouse |
| Clonality | Recombinant Mouse Monoclonal |
| Isotype | Mouse IgG1, kappa |
| Species Reactivity | Human (broad species reactivity predicted) |
| Application | IHC-P |
| Application Details | Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the Smooth Muscle Actin antibody should be determined by the researcher. |
| Localization | Cytoplasm |
| Immunogen | N-Terminal decapeptide of alpha smooth muscle isoform of actin was used as the immunogen for the Smooth Muscle Actin antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the Smooth Muscle Actin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Smooth Muscle Actin antibody is available for research use only. |
| Uniprot # | P62736 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/smooth-muscle-actin-antibody-racta21625-v9287 |
| Title | Smooth Muscle Actin Antibody |
| Description | Actin is a major component of the cytoskeleton and is present in most cell types. It is highly specific to actin from smooth muscles. <strong>This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells.</strong> This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin. |
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