• IHC staining of FFPE human prostate tissue with recombinant PMEPA1 antibody (clone rPMEPA1/6422). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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NSJ Bioreagents

V9286-100UG

Recombinant PMEPA1 Antibody / TMEPAI, 100 ug

Recombinant PMEPA1 Antibody / TMEPAI, 100 ug

$559.00 USD
$559.00 USD
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PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

Specifications

Catalog No V9286-100UG
Family Primary antibody
Qty 100 ug
Formulation 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format Purified
Clone rPMEPA1/6422
Host Animal Mouse
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG1, kappa
Species Reactivity Human
Application IHC-P
Application Details Immunohistochemistry (FFPE): 1-2ug/ml
Application Note Optimal dilution of the recombinant PMEPA1 antibody should be determined by the researcher.
Localization Cell surface, Cytoplasm
Immunogen Recombinant full-length human PMEPA1/TMEPAI protein was used as the immunogen for the recombinant PMEPA1 antibody.
Purity Protein A/G affinity
Storage Aliquot the recombinant PMEPA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This recombinant PMEPA1 antibody is available for research use only.
Uniprot # Q96W9
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/recombinant-pmepa1-antibody-tmepai-rpmepa16422-v9286
Title Recombinant PMEPA1 Antibody / TMEPAI
Description PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
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