NSJ Bioreagents
SKU:V9277-100UG
Recombinant HSP27 Antibody / HSPB1, 100 ug
Recombinant HSP27 Antibody / HSPB1, 100 ug
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HSP27, also referred to as Heat shock protein beta-1 (HSPB1), Estrogen-Regulated 24K protein, and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian -crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore, HSP27 may be useful in classifying various hormone sensitive tumors.
Specifications
| Catalog No | V9277-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | HSPB1/6490R |
| Host Animal | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, IHC-P |
| Application Details | Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the recombinant HSP27 antibody should be determined by the researcher. |
| Localization | Predominantly cytoplasmic with some nuclear |
| Immunogen | Recombinant human full-length HSP27 protein was used as the immunogen for the recombinant HSP27 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the recombinant HSP27 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This recombinant HSP27 antibody is available for research use only. |
| Uniprot # | P04792 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/recombinant-hsp27-antibody-hspb1-hspb16490r-v9277 |
| Title | Recombinant HSP27 Antibody / HSPB1 |
| Description | HSP27, also referred to as Heat shock protein beta-1 (HSPB1), Estrogen-Regulated 24K protein, and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian -crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore, HSP27 may be useful in classifying various hormone sensitive tumors. |
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